Description

(S)-3'-Hydroxycoclaurine Hydrochloride is a high-purity, chiral benzylisoquinoline alkaloid derivative, valued for its role as a critical synthetic intermediate and reference standard in advanced pharmaceutical research. Its primary significance lies in enabling the study and development of complex bioactive molecules, particularly within the fields of neuroscience and cardiovascular research. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on alkaloid chemistry and novel drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex natural products and potential therapeutic agents.
• Biochemical Research: Used as a reference standard and precursor in studies investigating alkaloid biosynthesis pathways and enzyme mechanisms.
• Neuroscience Research: Serves as a starting material for synthesizing compounds that interact with neurotransmitter systems for pharmacological evaluation.
• Academic & Contract Research: Employed in university and CRO settings for methodological development in asymmetric synthesis and natural product chemistry.
• Analytical Standard: Provides a high-purity benchmark for qualitative and quantitative analysis (e.g., HPLC, LC-MS) in quality control and method validation.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized, high-value chemical entities for client-specific projects.

Basic Information

Product Name	(S)-3'-Hydroxycoclaurine Hydrochloride
CAS No.	138666-04-3
Molecular Formula	C17H20ClNO4
Molecular Weight	337.80 g/mol
Synonyms	(S)-3'-Hydroxycoclaurine HCl; (S)-1-[(4-Hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolin-2-yl]methyl]-2,4,5-trihydroxybenzene hydrochloride; 3'-Hydroxycoclaurine hydrochloride, (S)-; Norcoclaurine-3'-ol hydrochloride; (S)-Norcoclaurine-3'-ol HCl
EINECS	Contact for details

Quality Control

Every batch of (S)-3'-Hydroxycoclaurine Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.