Description

N(3)-2'-Myristoyloxyethyl-N(6)-2'-Hydroxyethyl-1,8-Dioxotriethylenetetramine-N,N,N',N'-Tetraacetic Acid is a specialized, high-purity chelating agent derived from the triethylenetetramine backbone, offering enhanced lipophilicity and complexation properties. This compound is engineered to provide superior metal ion sequestration, particularly for transition and lanthanide metals, under challenging conditions. It is a critical intermediate and functional component for researchers and manufacturers in advanced pharmaceutical development, diagnostic imaging, and high-performance materials science.

Application

• Pharmaceutical Intermediate: Used in the synthesis of targeted contrast agents for magnetic resonance imaging (MRI) and other diagnostic applications.
• Metal Chelation Therapy: Serves as a potential active pharmaceutical ingredient (API) or precursor in formulations designed for heavy metal detoxification.
• Bioconjugation & Labeling: Facilitates the attachment of metal isotopes or reporter molecules to antibodies, peptides, and other biomolecules for research and diagnostics.
• Catalyst Ligand: Acts as a sophisticated ligand in homogeneous catalysis for fine chemical and pharmaceutical synthesis.
• Analytical Chemistry: Employed as a selective complexing agent in titrations, separations, and sensor technologies.
• Materials Science: Incorporated into polymers and coatings to impart metal-binding functionality or to control metal ion release.

Basic Information

Product Name	N(3)-2'-Myristoyloxyethyl-N(6)-2'-Hydroxyethyl-1,8-Dioxotriethylenetetramine-N,N,N',N'-Tetraacetic Acid
CAS No.	138420-02-7
Molecular Formula	C34H62N4O12
Molecular Weight	718.88 g/mol
Synonyms	Myristoyl-HOEt-DOTMA; N3-Myristoyl-N6-Hydroxyethyl-DOTMA; 1,8-Dioxo-1,4,8,11-tetraazacyclotetradecane-4,11-diacetic acid, 1-(2-(tetradecanoyloxy)ethyl)-8-(2-hydroxyethyl)-; DOTMA-C14-OH; 138420-02-7; Lipophilic DOTMA derivative; Myristoylated tetraacetic acid derivative; HOEt-Myr-DOTMA
EINECS	Contact for details

Quality Control

Our N(3)-2'-Myristoyloxyethyl-N(6)-2'-Hydroxyethyl-1,8-Dioxotriethylenetetramine-N,N,N',N'-Tetraacetic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.