Description

1,3-Dihexadecanoylamino-2-Valproyl-Propan-Ol is a specialized synthetic organic compound designed for advanced research and development applications. This molecule is valued for its unique structural features, combining long-chain fatty acid derivatives with a valproyl moiety, which can impart specific physicochemical properties. It serves as a critical intermediate or building block for researchers in the pharmaceutical and life sciences sectors. Target users include scientists developing novel drug delivery systems, lipid-based formulations, and bioactive probes.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Lipid Nanoparticle (LNP) Formulation: Used in the development and optimization of lipid-based delivery systems for nucleic acids (e.g., mRNA, siRNA) and other sensitive therapeutic agents.
• Bioconjugation & Probe Development: Acts as a functionalized linker or scaffold for creating chemical probes, diagnostic agents, or targeted conjugates in biochemical research.
• Excipient & Formulation Aid: Investigated for its potential as a novel excipient to modify the solubility, stability, or release profile of drug formulations.
• Biomedical Material Research: Explored in the synthesis of advanced biomaterials, such as functionalized polymers or coatings with specific biological interactions.
• Chemical Biology Studies: Employed as a tool compound to study lipid metabolism, protein-lipid interactions, or other complex biological processes.

Basic Information

Product Name	1,3-Dihexadecanoylamino-2-Valproyl-Propan-Ol
CAS No.	138404-96-3
Molecular Formula	C43H84N2O4
Molecular Weight	693.2 g/mol
Synonyms	1,3-Bis(palmitoylamino)-2-valproylpropan-2-ol; 2-Propanol, 1,3-bis(1-oxohexadecyl)amino-2-(2-propylpentanoyl)-; N,N'-Bis(hexadecanoyl)-2-valproyl-1,3-diamino-2-propanol; Valproyl-Di-C16 Lipid; Lipidoid V-C16; C16-Valproyl-C16 Amidite (research context); DG-Val-C16 (abbrev.)
EINECS	Contact for details

Quality Control

Our 1,3-Dihexadecanoylamino-2-Valproyl-Propan-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable for pharmaceutical intermediates, and our quality systems are designed to meet the stringent requirements of ISO 9001 standards. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.