Description

3-(2-Mercaptoethyl)Quinazoline-2,4(1H,3H)-Dione is a high-purity, specialized heterocyclic organic compound featuring a quinazoline-dione core with a reactive mercaptoethyl side chain. This molecular structure makes it a valuable key intermediate and building block for advanced synthesis in research and industrial chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins with unique thermal or mechanical properties.
• Bioconjugation Chemistry: The reactive thiol (-SH) group enables its use in bioconjugation techniques for labeling proteins, peptides, and other biomolecules.
• Chemical Synthesis Building Block: Provides a versatile scaffold for medicinal and combinatorial chemistry to create diverse libraries of compounds for screening.
• Research & Development: Essential for academic and industrial research exploring new chemical entities and reaction methodologies in organic chemistry.

Basic Information

Product Name	3-(2-Mercaptoethyl)Quinazoline-2,4(1H,3H)-Dione
CAS No.	138400-06-3
Molecular Formula	C11H10N2O2S
Molecular Weight	234.27 g/mol
Synonyms	2,4(1H,3H)-Quinazolinedione, 3-(2-mercaptoethyl)-; 3-(2-Mercaptoethyl)-2,4-dihydroxyquinazoline; 3-(2-Sulfanylethyl)-1H-quinazoline-2,4-dione; 2,4-Dihydroxy-3-(2-mercaptoethyl)quinazoline; 3-(2-Mercaptoethyl)quinazoline-2,4-diol; Quinazoline-2,4(1H,3H)-dione, 3-(2-mercaptoethyl)-
EINECS	Contact for details

Quality Control

Our 3-(2-Mercaptoethyl)Quinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to guarantee consistent quality and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.