Description

5-Oxa-2-Azaspiro[3.5]Nonane is a high-value, nitrogen-oxygen containing spirocyclic building block of significant interest in advanced organic synthesis. This heterocyclic compound serves as a critical scaffold for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, where its unique rigid structure enables the exploration of new chemical space and the modulation of biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets and other therapeutic areas requiring complex heterocycles.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	5-Oxa-2-Azaspiro[3.5]Nonane
CAS No.	138387-19-6
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	2-Aza-5-oxaspiro[3.5]nonane; 5-Oxa-2-azaspiro[3.5]nonane; 1-Oxa-4-azaspiro[4.4]nonane; Tetrahydro-1,4-oxazepine, spiro-; Spiro[3.5]nonane, 5-oxa-2-aza-; Oxazaspiro[3.5]nonane; 138387-19-6 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Oxa-2-Azaspiro[3.5]Nonane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While typically supplied as a high-purity research grade, production can be aligned with cGMP guidelines for advanced pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.