Description

1-Azaspiro[4.4]Non-3-Ene-3-Carboxylicacid,4-Amino-1-Methyl-2-Oxo-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex biological pathways. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Protease Inhibitor Development: Potential precursor in the development of inhibitors for various enzymatic processes.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological mechanisms.
• Custom Synthesis: Employed in contract research and manufacturing (CRAM) for client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	1-Azaspiro[4.4]Non-3-Ene-3-Carboxylicacid,4-Amino-1-Methyl-2-Oxo-(9Ci)
CAS No.	138377-78-3
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	4-Amino-1-methyl-2-oxo-1-azaspiro[4.4]non-3-ene-3-carboxylic acid; 1-Azaspiro[4.4]non-3-ene-3-carboxylic acid, 4-amino-1-methyl-2-oxo-; 138377-78-3; 4-Amino-1-methyl-2-oxo-1-azaspiro[4.4]non-3-ene-3-carboxylate; 1-Methyl-4-amino-2-oxo-1-azaspiro[4.4]non-3-ene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[4.4]Non-3-Ene-3-Carboxylicacid,4-Amino-1-Methyl-2-Oxo-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.