Description

1,8-Naphthyridine-3-Carboxamide, 1,2-Dihydro-4-Hydroxy-2-Oxo-1-Phenyl- n-4-Pyridinyl-, Hydrate (5:3) is a high-purity, complex heterocyclic organic compound with significant pharmaceutical research value. This specialized chemical serves as a critical advanced intermediate or building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially for central nervous system (CNS) or anti-infective targets.
• Chemical Synthesis Research: Used in academic and industrial laboratories to study novel organic reactions and construct complex heterocyclic systems.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or core structure in the synthesis pathway of potential APIs.
• Biochemical Research: May be utilized as a ligand or probe in biochemical assays to study enzyme inhibition or receptor binding.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialized fine chemicals and advanced materials.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxamide, 1,2-Dihydro-4-Hydroxy-2-Oxo-1-Phenyl- n-4-Pyridinyl-, Hydrate (5:3)
CAS No.	138304-91-3
Molecular Formula	C20H16N4O4 • (3/5)H2O
Molecular Weight	Contact for details
Synonyms	1,2-Dihydro-4-hydroxy-2-oxo-1-phenyl-N-4-pyridinyl-1,8-naphthyridine-3-carboxamide hydrate (5:3); 1-Phenyl-1,2-dihydro-4-hydroxy-2-oxo-N-(pyridin-4-yl)-1,8-naphthyridine-3-carboxamide hydrate; 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl-N-4-pyridinyl-, hydrate (5:3); GSK-3 Inhibitor IX hydrate; CHIR 99021 hydrate; CT99021 hydrate; Aminopyrimidine derivative hydrate; 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-N-(1-methylethyl)-3-pyridinecarboxamide (Related compound search term).
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carboxamide derivative is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Corresponds to hydrate ratio
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.