Description

1,1-Bis(4-Hydroxyphenyl)-2-Iodo-2-Phenylethylene is a specialized iodinated phenolic compound with a unique molecular structure that serves as a valuable intermediate in advanced organic synthesis. Its significance lies in its role as a key building block for the development of complex molecules, particularly in pharmaceutical research and material science. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to create novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting hormonal pathways or requiring iodinated aromatic structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its phenolic and ethylene backbone can be modified for specific biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced organic electronic materials due to its rigid, conjugated structure and functional groups.
• Polymer Modification: Employed to introduce phenolic and iodinated moieties into polymer chains, enhancing properties like flame retardancy, adhesion, or UV stability.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry and for scaling up novel synthetic routes.

Basic Information

Product Name	1,1-Bis(4-Hydroxyphenyl)-2-Iodo-2-Phenylethylene
CAS No.	138109-87-2
Molecular Formula	C20H15IO2
Molecular Weight	414.24 g/mol
Synonyms	2-Iodo-1,1-bis(4-hydroxyphenyl)-1-phenylethylene; 1,1-Bis(4-hydroxyphenyl)-2-iodo-2-phenylethane (common misnomer); 4,4'-(1-Iodo-2-phenylethene-1,1-diyl)diphenol; Iodinated bisphenol derivative; (2-Iodo-1,1-diphenylethylene-4,4'-diol); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 1,1-Bis(4-Hydroxyphenyl)-2-Iodo-2-Phenylethylene undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR and NMR), and impurity profiles is provided with each shipment to support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.