Description

2(1H)-Quinolinone,3-Iodo-1-Methyl-(9Ci) is a halogenated quinolinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic placement of the iodine atom, which serves as an excellent handle for further functionalization via cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinolinone scaffold's bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: The iodine substituent makes it an ideal substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to introduce complex aryl, alkynyl, or alkenyl groups.
• Ligand Synthesis: Utilized for the preparation of specialized nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Item	Detail
Product Name	2(1H)-Quinolinone,3-Iodo-1-Methyl-(9Ci)
CAS No.	138037-41-9
Molecular Formula	C10H8INO
Molecular Weight	285.08 g/mol
Synonyms	3-Iodo-1-methylquinolin-2(1H)-one; 1-Methyl-3-iodoquinolin-2(1H)-one; 3-Iodo-1-methyl-2(1H)-quinolinone; 3-Iodo-1-methyl-1H-quinolin-2-one; 1-Methyl-3-iodo-1H-quinolin-2-one; 3-Iodo-N-methylcarbostyril; 9CI-138037-41-9
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone,3-Iodo-1-Methyl-(9Ci) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.