Description

(S)-2-Amino-3-Quinolin-4-Yl-Propionic Acid CAS NO 137855-78-8 is a high-purity, non-proteinogenic amino acid derivative featuring a quinoline moiety. This chiral building block is of significant value in pharmaceutical research and development, particularly for the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide mimetics, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in oncology and neurology.
• Peptidomimetics Design: Used to incorporate the quinoline pharmacophore into peptide backbones to enhance stability, bioavailability, and target binding affinity.
• Enzyme Inhibitor Synthesis: Serves as a core structure in designing inhibitors for various enzymes, including kinases and proteases.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying biological pathways and target engagement.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthetic routes.
• Academic & Contract Research: Essential for fundamental organic chemistry research and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	(S)-2-Amino-3-Quinolin-4-Yl-Propionic Acid
CAS No.	137855-78-8
Molecular Formula	C₁₂H₁₂N₂O₂
Molecular Weight	216.24 g/mol
Synonyms	(S)-2-Amino-3-(quinolin-4-yl)propanoic acid; (S)-4-Quinolin-4-yl-alanine; L-4-Quinolylalanine; (S)-3-(4-Quinolyl)alanine; (2S)-2-Amino-3-(4-quinolyl)propanoic acid; 4-Quin-Ala-OH; (S)-α-Amino-4-quinolinepropionic acid; 137855-78-8
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-Quinolin-4-Yl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.