Description

3-Chloromethyl-2,7-Dichloroquinoline is a versatile and highly functionalized quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring reactive chloromethyl and chloro substituents, makes it an essential building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is particularly valuable for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those with quinoline-based pharmacophores for antimicrobial, anticancer, or anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline scaffold contributes to biological efficacy.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of novel organic electronic materials, ligands for catalysis, or fluorescent dyes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Chloromethyl-2,7-Dichloroquinoline
CAS No.	137776-95-5
Molecular Formula	C10H6Cl3N
Molecular Weight	246.52 g/mol
Synonyms	2,7-Dichloro-3-(chloromethyl)quinoline; 3-(Chloromethyl)-2,7-dichloroquinoline; Quinoline, 3-(chloromethyl)-2,7-dichloro-; 2,7-Dichloro-3-chloromethylquinoline
EINECS	Contact for details

Quality Control

Our 3-Chloromethyl-2,7-Dichloroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is accompanied by a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable, ensuring the material meets the stringent requirements for use in pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.