Description

(2S)-2-Phenyl-Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stereochemical complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of central nervous system (CNS) active drugs, including potential antidepressants and antipsychotics.
• Ligand for Asymmetric Catalysis: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for complex, high-value chiral molecules.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological studies in universities and corporate R&D labs.

Basic Information

Product Name	(2S)-2-Phenyl-Piperazine
CAS No.	137766-74-6
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(S)-2-Phenylpiperazine; (S)-2-Phenyl-piperazine; (S)-2-Phenylpiperazine; L-2-Phenylpiperazine; (2S)-2-Phenylpiperazine; 2-Phenylpiperazine, (2S)-; 1,4-Diazacyclohexane, 2-phenyl-, (2S)-; Piperazine, 2-phenyl-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-Phenyl-Piperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.