Description

2-(Aminopropyl-1-Oxyl)-4-((5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carboxamido)Benzoic Acid is a specialized synthetic intermediate of significant interest in advanced organic synthesis and pharmaceutical research. Its complex molecular architecture, featuring a benzoic acid core linked to a tetramethyl-tetralin moiety via an amide bond and an aminopropyloxyl nitroxide radical, makes it a valuable precursor for the development of novel compounds. This high-purity chemical is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting nuclear receptors or requiring radical chemistry.
• Spin Labeling Agent: The stable nitroxide radical (aminopropyl-1-oxyl) makes it useful in Electron Paramagnetic Resonance (EPR) spectroscopy for studying biomolecular structure and dynamics.
• Advanced Material Research: Used in the development of functional polymers, organic semiconductors, or materials with specific magnetic properties.
• Agrochemical Synthesis: Acts as a precursor for creating new active ingredients with potential herbicidal or insecticidal properties, leveraging its complex hydrophobic structure.
• Chemical Biology Probe: Employed to label proteins or other biomolecules for mechanistic studies due to its radical tag and reactive functional groups.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	2-(Aminopropyl-1-Oxyl)-4-((5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carboxamido)Benzoic Acid
CAS No.	137757-03-0
Molecular Formula	C26H34N2O4
Molecular Weight	438.56 g/mol
Synonyms	4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]-2-(3-aminopropoxy)benzoic acid; 2-(3-Aminopropoxy)-4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthoyl)amino]benzoic acid; TTN Benzoic Acid Derivative; AMT-Naphthamide; Nitroxide-labeled Tetralin Amide; CAS 137757-03-0; 2-(3-Aminopropoxy)-4-[[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)carbonyl]amino]benzoic acid
EINECS	Contact for details

Quality Control

Our production of 2-(Aminopropyl-1-Oxyl)-4-((5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carboxamido)Benzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.