Description

Quinoline, 6-Fluoro-3-Methyl- (9Ci) is a fluorinated and methylated quinoline derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing and electron-donating substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and pharmaceutical developers for the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors, antimicrobial agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the quinoline scaffold contributes to efficacy and selectivity.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), dyes, and other functional organic materials due to its modifiable fluorophore core.
• Chemical Research & Development: Employed as a standard or building block in method development, catalysis studies, and the synthesis of complex natural product analogs.
• Ligand and Catalyst Preparation: The nitrogen heterocycle can be utilized to create novel ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	Quinoline, 6-Fluoro-3-Methyl- (9Ci)
CAS No.	137595-46-1
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	6-Fluoro-3-methylquinoline; 3-Methyl-6-fluoroquinoline; 6-Fluoro-3-methyl-quinoline; Quinoline, 6-fluoro-3-methyl-; 137595-46-1; 6-Fluoro-3-methylchinolin; 3-Methyl-6-fluorochinolin
EINECS	Contact for details

Quality Control

Our Quinoline, 6-Fluoro-3-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures reliable material for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.