Description

(R)-(-)-2,2'-Bis(p-Toluenesulfonyloxy)-1,1'-Binaphthalene CAS NO 137568-37-7 is a high-value chiral binaphthyl derivative, specifically a tosylated (R)-BINOL compound. This chemical serves as a crucial chiral auxiliary and building block in asymmetric synthesis, enabling the creation of enantiomerically pure pharmaceuticals and advanced materials. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing chiral catalysts, ligands, and active pharmaceutical ingredients (APIs).

Application

• Chiral Ligand Synthesis: A key precursor for preparing enantioselective catalysts and ligands used in asymmetric hydrogenation, coupling, and oxidation reactions.
• Pharmaceutical Intermediate: Employed in the synthesis of enantiomerically pure drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Material Science Research: Used to develop chiral polymers, liquid crystals, and molecular recognition systems with specific optical properties.
• Asymmetric Catalysis Development: Serves as a starting material for creating novel organocatalysts and metal-complex catalysts for green chemistry applications.
• Analytical Standard: Acts as a reference standard for chiral chromatography and spectroscopic analysis in quality control laboratories.

Basic Information

Item	Detail
Product Name	(R)-(-)-2,2'-Bis(p-Toluenesulfonyloxy)-1,1'-Binaphthalene
CAS No.	137568-37-7
Molecular Formula	C34H26O6S2
Molecular Weight	610.69 g/mol
Synonyms	(R)-(-)-2,2'-Bis(tosyloxy)-1,1'-binaphthyl; (R)-BINOL Ditosylate; (R)-2,2'-Di-p-toluenesulfonyloxy-1,1'-binaphthalene; (R)-DTB; (R)-1,1'-Bi-2-naphthol Ditosylate; (R)-(-)-1,1'-Binaphthalene-2,2'-diyl bis(4-methylbenzenesulfonate); (R)-BINOL-OTs; (R)-2,2'-Bis(4-methylbenzenesulfonyloxy)-1,1'-binaphthalene
EINECS	Contact for details

Quality Control

Our (R)-(-)-2,2'-Bis(p-Toluenesulfonyloxy)-1,1'-Binaphthalene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided and available upon request to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when opening. Keep the container tightly sealed in a desiccator when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.