Description

(3R,4S)-Tetrahydrofuran-3,4-Diamine Dihydrochloride is a high-purity, chiral diamine derivative with significant utility in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and fine chemicals, particularly where stereochemical control is paramount. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and neurological drug candidates.
• Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enabling enantioselective transformations in fine chemical production.
• Polymer Modification: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Agrochemical Synthesis: Employed in the research and development of novel, stereochemically defined pesticides and herbicides.
• Chemical Biology Probe Development: Utilized as a scaffold for designing molecular probes and inhibitors to study biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and process chemistry.

Basic Information

Product Name	(3R,4S)-Tetrahydrofuran-3,4-Diamine Dihydrochloride
CAS No.	137277-16-8
Molecular Formula	C4H10N2O · 2HCl
Molecular Weight	187.07 g/mol
Synonyms	(3R,4S)-3,4-Diaminotetrahydrofuran Dihydrochloride; (3R,4S)-Tetrahydro-3,4-furandiamine Dihydrochloride; (3R,4S)-3,4-Diaminotetrahydrofuran Hydrochloride; (3R,4S)-3,4-Diaminofuranidine Dihydrochloride; (3R-cis)-Tetrahydro-3,4-furandiamine Dihydrochloride; 3,4-Diaminotetrahydrofuran Dihydrochloride (3R,4S-isomer); 137277-16-8; THF-3,4-diamine dihydrochloride (3R,4S)
EINECS	Contact for details

Quality Control

Our (3R,4S)-Tetrahydrofuran-3,4-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.