Description

(1R,2S)-cis-2-Aminocyclopentanol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its defined stereochemistry, which is crucial for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Serves as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetics Research: Incorporated into the backbone of cyclic peptide analogs to study structure-activity relationships and enhance metabolic stability.
• Catalyst Design: A precursor for developing novel chiral organocatalysts or metal-complexing agents used in fine chemical production.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereochemically complex molecules.

Basic Information

Product Name	(1R,2S)-cis-2-Aminocyclopentanol Hydrochloride
CAS No.	137254-03-6
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(1R,2S)-(-)-2-Amino-1-cyclopentanol hydrochloride; cis-(-)-2-Amino-1-cyclopentanol hydrochloride; (1R,2S)-2-Aminocyclopentanol HCl; (1R,2S)-(-)-2-Aminocyclopentanol hydrochloride; (1R,2S)-cis-1-Amino-2-hydroxycyclopentane hydrochloride; (1R,2S)-2-Amino-cyclopentan-1-ol hydrochloride; (1R,2S)-1-Amino-2-hydroxycyclopentane hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2S)-cis-2-Aminocyclopentanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.