Description

Cyclopropanecarboxamide, 1-Fluoro-n-(6-Fluoro-3-Pyridinyl)- (9Ci) is a high-purity fluorinated pyridine derivative and cyclopropane carboxamide, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures, particularly for active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs and cyclopropane rings to enhance biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluoropyridine moiety contributes to efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Precursor: Potential use in the development of specialized ligands for catalytic systems or as a precursor for organometallic complexes.
• Material Science Applications: Exploration into the synthesis of fluorinated polymers or advanced materials with specific electronic or surface properties.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxamide, 1-Fluoro-n-(6-Fluoro-3-Pyridinyl)- (9Ci)
CAS No.	137081-16-4
Molecular Formula	C9H7F2N2O
Molecular Weight	197.16 g/mol
Synonyms	1-Fluoro-N-(6-fluoropyridin-3-yl)cyclopropanecarboxamide; N-(6-Fluoro-3-pyridinyl)-1-fluorocyclopropanecarboxamide; 1-Fluoro-N-(6-fluoro-3-pyridinyl)cyclopropanecarboxamide; Cyclopropanecarboxamide, 1-fluoro-N-(6-fluoro-3-pyridinyl)-; 137081-16-4; 1-Fluoro-N-(6-fluoropyridin-3-yl)cyclopropane-1-carboxamide
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxamide, 1-Fluoro-n-(6-Fluoro-3-Pyridinyl)- (9Ci) is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.