Description

7-Bromo-2-Chloroquinoline-3-Carboxaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Serves as a building block for developing new pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and in the synthesis of advanced organic electronic materials.
• Chemical Synthesis: Functions as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a formyl group donor for constructing complex heterocycles.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis of target molecules.

Basic Information

Product Name	7-Bromo-2-Chloroquinoline-3-Carboxaldehyde
CAS No.	136812-31-2
Molecular Formula	C10H5BrClNO
Molecular Weight	270.51 g/mol
Synonyms	2-Chloro-7-bromoquinoline-3-carboxaldehyde; 3-Formyl-7-bromo-2-chloroquinoline; 7-Bromo-2-chloro-3-quinolinecarboxaldehyde; 7-Bromo-2-chloroquinoline-3-carbaldehyde; 136812-31-2; Quinoline-3-carboxaldehyde, 7-bromo-2-chloro-; 2-Chloro-7-bromo-3-quinolinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Chloroquinoline-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.