Description

2-Chloro-8-Methylquinoline-3-Carbonitrile is a versatile and high-value quinoline derivative that serves as a critical synthetic intermediate. Its molecular structure makes it a valuable building block for constructing more complex heterocyclic compounds, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in facilitating targeted molecular synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging its quinoline core.
• Material Science Research: Serves as a building block for creating organic ligands, dyes, and photoactive materials in advanced material studies.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst and Ligand Preparation: Potential use in the development of specialized catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-8-Methylquinoline-3-Carbonitrile
CAS No.	136812-21-0
Molecular Formula	C11H7ClN2
Molecular Weight	202.64 g/mol
Synonyms	2-Chloro-8-methylquinoline-3-carbonitrile; 3-Cyano-2-chloro-8-methylquinoline; 8-Methyl-2-chloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 2-chloro-8-methyl-; 136812-21-0; 2-Chloro-8-methyl-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Methylquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.