Description

(+/-)-3,4-Methylenedioxyamphetamine-D5 is a deuterated internal standard of the psychoactive compound MDA, specifically designed for analytical applications. This high-purity, isotopically labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily used by analytical chemists and forensic scientists in pharmaceutical research, forensic toxicology, and clinical diagnostics for method development and validation.

Application

• Quantitative Mass Spectrometry: Serves as a critical internal standard for the precise quantification of MDA and related substances in complex biological matrices using GC-MS or LC-MS/MS.
• Forensic Toxicology: Used in the analysis of human samples (e.g., blood, urine, hair) for the detection and confirmation of drug use in criminal investigations and workplace testing.
• Clinical Research & Diagnostics: Enables accurate measurement of drug metabolites in pharmacokinetic studies and clinical trials.
• Pharmaceutical Analysis: Supports impurity profiling, stability testing, and method validation in the development of controlled substances or related pharmaceutical agents.
• Reference Material: Acts as a certified reference material (CRM) for calibrating analytical instruments and ensuring laboratory compliance with ISO/IEC 17025 standards.
• Metabolite Studies: Facilitates research into the metabolic pathways and biotransformation of amphetamine derivatives.

Basic Information

Product Name	(+/-)-3,4-Methylenedioxyamphetamine-D5
CAS No.	136765-42-9
Molecular Formula	C10H8D5NO2
Molecular Weight	181.24 g/mol
Synonyms	MDA-D5; 3,4-Methylenedioxyamphetamine-D5; (±)-MDA-D5; 1-(1,3-Benzodioxol-5-yl)-2-aminopropane-D5; 3,4-(Methylenedioxy)amphetamine-D5; 3,4-Methylenedioxyphenylisopropylamine-D5; N-Methyl-3,4-methylenedioxyamphetamine-D5 (common misnomer, verify structure); Amphetamine, 3,4-methylenedioxy-, D5-labeled
EINECS	Contact for details

Quality Control

Every batch of (+/-)-3,4-Methylenedioxyamphetamine-D5 is produced and analyzed under strict quality management protocols to ensure exceptional purity and isotopic enrichment, critical for its role as an internal standard. Our products undergo rigorous quality testing, including NMR, HPLC, and mass spectrometry, to ensure compliance with the stringent requirements of analytical reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.