Description

Methaqualone-D7 CAS NO 136765-41-8 is a deuterated analog of methaqualone, where seven hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This high-purity, isotopically labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is primarily required by analytical laboratories, forensic science institutions, and pharmaceutical R&D departments for applications in drug metabolism studies, pharmacokinetic research, and regulatory compliance testing.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of methaqualone and its metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Forensic Toxicology: Used in confirmatory testing and method development for the accurate identification and measurement of methaqualone in forensic casework.
• Pharmaceutical Research: Facilitates drug metabolism and pharmacokinetic (DMPK) studies, enabling the tracking of the parent drug's fate in the body.
• Clinical Research: Supports studies investigating drug abuse, therapeutic monitoring, and clinical toxicology.
• Reference Material: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating testing methodologies.
• Regulatory Compliance Testing: Essential for laboratories adhering to FDA, EMA, or other regulatory guidelines that require isotope-dilution mass spectrometry for definitive analysis.

Basic Information

Product Name	Methaqualone-D7
CAS No.	136765-41-8
Molecular Formula	C16H7D7N2O
Molecular Weight	263.33 g/mol
Synonyms	2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone-D7; 2-Methyl-3-o-tolyl-4(3H)-quinazolinone-D7; Deuterated Methaqualone; Methaqualone-d7; [2H7]-Methaqualone; 4-Quinazolinone, 2-methyl-3-(2-methylphenyl)-, D7-; Qz-D7
EINECS	Contact for details

Quality Control

Our Methaqualone-D7 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical stability, meeting the stringent requirements of analytical reference standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (Atom % D), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with ISO/IEC 17025 standards for testing laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the original container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.