Description

Benzoylecgonine Ethyl Ester-D3 is a stable isotope-labeled internal standard, specifically the deuterated ethyl ester derivative of benzoylecgonine. This compound is critically important for ensuring the accuracy and reliability of quantitative analytical methods, particularly in forensic and clinical toxicology. It is an essential reference material for laboratories conducting precise mass spectrometry-based analyses of cocaine and its metabolites.

Application

• Quantitative Internal Standard for LC-MS/MS and GC-MS: Used for the accurate quantification of benzoylecgonine and cocaine in complex biological matrices such as urine, blood, and hair.
• Forensic Toxicology Analysis: Critical for method development and validation in crime labs and forensic institutions for drug testing and legal proceedings.
• Clinical Research and Diagnostics: Supports studies on drug metabolism, pharmacokinetics, and the development of diagnostic assays for substance abuse monitoring.
• Pharmaceutical Impurity Testing: Can be employed in the analysis of pharmaceutical products for controlled substance impurities or adulterants.
• Method Development and Validation: Serves as a key component in establishing robust, reproducible, and compliant analytical procedures according to FDA, ISO, or other regulatory guidelines.
• Quality Control in Reference Material Production: Used in the calibration and verification of certified reference materials (CRMs) for forensic and clinical markets.

Basic Information

Item	Details
Product Name	Benzoylecgonine Ethyl Ester-D3
CAS No.	136765-30-5
Molecular Formula	C18H20D3NO4
Molecular Weight	Contact for details
Synonyms	Benzoylecgonine Ethyl Ester-d3; Cocaine Metabolite Ethyl Ester-d3; 3-Benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Ethyl Ester-d3; BEE-d3; Ecgonine Ethyl Ester Benzoate-d3; Benzoylecgonine Ethyl Ester (Deuterated); BZE Ethyl Ester-d3; Deuterated Benzoylecgonine Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Benzoylecgonine Ethyl Ester-D3 is manufactured and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical reference standards. Comprehensive testing includes identity confirmation, assay determination, and isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.