Description

.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-2,3-Dideoxy-2-(Methoxymethyl)-4-o-(Phenylmethyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique anhydro sugar derivative structure. This compound is critical for the synthesis of complex nucleoside analogs and other bioactive molecules, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for the production of antiviral agents, enzyme inhibitors, and other specialized therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing carbohydrate-active enzymes.
• Glycochemistry: Serves as a protected sugar derivative for the construction of complex oligosaccharides and glycoconjugates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic candidates targeting viral polymerases.
• Process Development: Used in scaling up routes for the production of active pharmaceutical ingredients (APIs) requiring specialized carbohydrate motifs.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating custom-designed molecules with specific stereochemical configurations.

Basic Information

Item	Detail
Product Name	.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-2,3-Dideoxy-2-(Methoxymethyl)-4-o-(Phenylmethyl)-
CAS No.	136759-93-8
Molecular Formula	C15H20O5
Molecular Weight	280.32 g/mol
Synonyms	1,6-Anhydro-2,3-dideoxy-2-(methoxymethyl)-4-O-benzyl-β-D-ribo-hexopyranose; 4-O-Benzyl-1,6-anhydro-2,3-dideoxy-2-C-(methoxymethyl)-β-D-ribo-hexopyranose; 4-O-Benzyl-2-C-(methoxymethyl)-1,6-anhydro-2,3-dideoxy-β-D-ribo-hexopyranose; Benzyl 1,6-anhydro-2,3-dideoxy-2-C-(methoxymethyl)-β-D-ribo-hexopyranoside; 136759-93-8; Anhydro sugar derivative; Protected ribo-hexopyranose intermediate.
EINECS	Contact for details

Quality Control

Our .Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-2,3-Dideoxy-2-(Methoxymethyl)-4-o-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.