Description

(R)-6-Methoxy-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is a chiral, non-racemic tetralin derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized structure, enabling the precise construction of complex molecules with specific biological activity. This high-purity intermediate is essential for research and development in the pharmaceutical industry, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, including central nervous system (CNS) drugs and cardiovascular medications.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective synthesis to introduce the (R)-configuration into target molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and high-value fragrance compounds requiring specific stereochemistry.
• Academic & Contract Research: Serves as a valuable reagent in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial-scale production of chiral APIs.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(R)-6-Methoxy-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid
CAS No.	136759-35-8
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	(R)-6-Methoxy-1,2,3,4-tetrahydro-2-naphthoic Acid; (2R)-6-Methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic Acid; (R)-6-Methoxy-tetralin-2-carboxylic Acid; (R)-MTCA; (R)-6-Methoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylic Acid; (2R)-6-Methoxy-3,4-dihydro-2H-naphthalene-2-carboxylic Acid; (R)-6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-carbonsäure (German)
EINECS	Contact for details

Quality Control

Our (R)-6-Methoxy-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.