Description

S-(4-Methoxybenzyl)Thioglycolylaminoethylsulfonylethyl-4-Nitrophenyl Carbonate is a specialized organic synthesis intermediate featuring a reactive carbonate ester group activated by a nitrophenyl leaving group. This compound is valued for its role in the controlled formation of amide or carbamate linkages, particularly in complex molecule assembly and bioconjugation strategies. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors for the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring targeted drug delivery systems.
• Bioconjugation Reagent: Used for coupling biomolecules (e.g., peptides, proteins, antibodies) with drugs, dyes, or polymers to create antibody-drug conjugates (ADCs) or diagnostic probes.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of specialty polymers with tailored degradation profiles.
• Proteomics Research: Employed in chemical proteomics for labeling and studying protein function and interactions.
• Material Science: Applied in surface modification and the creation of functionalized materials for biomedical applications.

Basic Information

Product Name	S-(4-Methoxybenzyl)Thioglycolylaminoethylsulfonylethyl-4-Nitrophenyl Carbonate
CAS No.	136743-24-3
Molecular Formula	C20H22N2O8S2
Molecular Weight	482.53 g/mol
Synonyms	4-Nitrophenyl S-(4-Methoxybenzyl)thioglycolylaminoethylsulfonylethyl Carbonate; p-Nitrophenyl Carbonate of S-(4-Methoxybenzyl)thioglycolylaminoethylsulfonylethanol; MBTG-NP Carbonate; (4-Methoxybenzyl)sulfonylethyl 4-nitrophenyl carbonate derivative; Thioglycolic acid S-(4-methoxybenzyl) amide ethylsulfone ethyl 4-nitrophenyl carbonate
EINECS	Contact for details

Quality Control

Our S-(4-Methoxybenzyl)Thioglycolylaminoethylsulfonylethyl-4-Nitrophenyl Carbonate is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.