Description

(-)-1,2(2R,5R)-2,5-(Dimethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate is a high-purity, chiral organorhodium complex widely recognized for its exceptional catalytic performance in asymmetric synthesis. This compound matters because it serves as a highly efficient and selective catalyst, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel chiral molecules.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective hydrogenation of prochiral olefins, enamides, and ketones in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Production: Key for manufacturing chiral active pharmaceutical ingredients (APIs), including those for cardiovascular, central nervous system, and antiviral drugs.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the synthesis of high-value chiral compounds for flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: A vital tool in methodological development for new asymmetric catalytic transformations in both academic and corporate research laboratories.
• Process Chemistry Optimization: Employed for scaling up efficient and cost-effective catalytic processes from lab to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	(-)-1,2(2R,5R)-2,5-(Dimethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate
CAS No.	136705-75-4
Molecular Formula	C₂₀H₂₈F₃O₃P Rh S
Molecular Weight	539.37 g/mol
Synonyms	(-)-[Rh((R,R)-Me-DuPhos)(COD)]OTf; (R,R)-Me-DuPhos Rhodium(I) Triflate Catalyst; Rh-(R,R)-Me-DuPhos-COD-OTf; [Rh(COD)((R,R)-Me-DuPhos)]OTf; (R,R)-2,5-Dimethylphospholano Benzene Cyclooctadiene Rhodium(I) Trifluoromethanesulfonate; Rh-MeDuPhos Catalyst; Asymmetric Hydrogenation Catalyst with Me-DuPhos Ligand; Rh(COD)((R,R)-Me-DuPhos)OTf
EINECS	Contact for details

Quality Control

Our (-)-1,2(2R,5R)-2,5-(Dimethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and enantiomeric excess of the ligand system. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Moisture Content (KF)	< 1.0%
Solubility	Soluble in dichloromethane, acetone, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.