Description

1,2-Bis((2R,5R)-2,5-Diethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate is a high-purity, chiral organorhodium complex widely recognized as a highly effective asymmetric hydrogenation catalyst. Its value lies in enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals and fine chemicals. This catalyst is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in synthetic processes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in complex molecule synthesis.
• Pharmaceutical Intermediate Synthesis: Production of chiral active pharmaceutical ingredients (APIs) and key building blocks for drug discovery and development.
• Agrochemical Manufacturing: Synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Creation of high-value chiral compounds for flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable tool for methodology development in organic synthesis and catalysis studies.
• Process Chemistry Optimization: Scaling up asymmetric transformations from laboratory to pilot plant and commercial production.

Basic Information

Product Name	1,2-Bis((2R,5R)-2,5-Diethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate
CAS No.	136705-71-0
Molecular Formula	C₂₄H₄₃F₃O₃P₂RhS
Molecular Weight	657.50 g/mol
Synonyms	(R,R)-Et-DuPhos Rhodium(I) Cyclooctadiene Triflate; [Rh((R,R)-Et-DuPhos)(COD)]OTf; (R,R)-1,2-Bis(2,5-Diethylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; Rh-(R,R)-Et-DuPhos-COD-OTf; DuPhos Rhodium Catalyst; Chiral Rhodium(I) DuPhos Complex; Asymmetric Hydrogenation Rhodium Catalyst; (2R,5R)-1,1'-(-1,2-Ethanediyl)bis[2,5-diethylphospholane](1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our 1,2-Bis((2R,5R)-2,5-Diethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate is manufactured under strict quality systems to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including chiral purity assessment and metal content analysis, to meet the exacting standards required for asymmetric synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee) of the ligand, and specific performance data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool environment. Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a controlled, dry atmosphere and the contents used promptly to maintain optimal catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Rhodium Content	15.0 - 16.0 %
Chiral Purity (Ligand ee)	≥ 98.0%
Solubility	Soluble in dichloromethane, THF; sparingly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.