Description

(2S)-1-tert-Butoxypropan-2-Ol CAS NO 136656-76-3 is a chiral, non-racemic chemical intermediate of significant value in asymmetric synthesis. Its structure, featuring a protected hydroxyl group, makes it a versatile building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity chiral precursors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Asymmetric Catalyst Ligand Precursor: Used in the development and manufacture of chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry R&D.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with controlled stereochemistry.

Basic Information

Product Name	(2S)-1-tert-Butoxypropan-2-Ol
CAS No.	136656-76-3
Molecular Formula	C7H16O2
Molecular Weight	132.20 g/mol
Synonyms	(S)-1-(tert-Butoxy)propan-2-ol; (S)-1-tert-Butoxy-2-propanol; (2S)-1-(1,1-Dimethylethoxy)-2-propanol; (S)-2-Propanol, 1-(1,1-dimethylethoxy)-; (S)-1-tert-Butoxypropan-2-ol; (S)-O-tert-Butylglycidol; Chiral tert-Butyl glycidyl ether alcohol; (S)-Tert-Butyl Glycidyl Ether Hydrolysis Product
EINECS	Contact for details

Quality Control

Our (2S)-1-tert-Butoxypropan-2-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.