Description

(2R,3R)-2,3-Diaminobutane-1,4-Diol CAS NO 136598-06-6 is a high-purity chiral diamine diol building block, a versatile intermediate prized for its defined stereochemistry. This compound is essential for the synthesis of complex molecules where precise spatial orientation is critical for biological activity or material properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, ligand development, and polymer chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, antibiotic, and anticancer drug candidates.
• Asymmetric Catalyst & Ligand Synthesis: Serves as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Research: Building block for the synthesis of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Polymer & Material Science: Monomer for the production of specialty polyamides, polyurethanes, and epoxy curing agents, imparting unique thermal and mechanical properties.
• Chelating Agent Precursor: Used to synthesize multidentate chelating agents for metal ion sequestration and catalysis.
• Bioconjugation & Linker Chemistry: Utilized in the design of cross-linkers and spacers for bioconjugation applications in diagnostics and biotherapeutics.

Basic Information

Product Name	(2R,3R)-2,3-Diaminobutane-1,4-Diol
CAS No.	136598-06-6
Molecular Formula	C4H12N2O2
Molecular Weight	120.15 g/mol
Synonyms	(2R,3R)-(-)-2,3-Diamino-1,4-butanediol; (2R,3R)-2,3-Diamino-1,4-butanediol; (2R,3R)-1,4-Butanediol, 2,3-diamino-; D-(-)-threo-2,3-Diamino-1,4-butanediol; (2R,3R)-(-)-1,4-Diamino-2,3-butanediol; (2R,3R)-DAB; Chiral DAB; threo-2,3-Diamino-1,4-butanediol (specified enantiomer)
EINECS	Contact for details

Quality Control

Our (2R,3R)-2,3-Diaminobutane-1,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.