Description

trans-Methyl 2-Aminocyclopentanecarboxylate Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis. Its defined stereochemistry and protected amino acid functionality make it a critical intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, neurological agents, and other small-molecule therapeutics.
• Peptidomimetics Research: Serves as a constrained, cyclic amino acid analog in the design and development of novel peptide-based drugs.
• Agrochemical Synthesis: Building block for creating chiral active ingredients in advanced crop protection products.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services targeting specific client R&D projects.

Basic Information

Product Name	trans-Methyl 2-Aminocyclopentanecarboxylate Hydrochloride
CAS No.	136237-67-7
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	trans-Methyl 2-aminocyclopentanecarboxylate HCl; Methyl (1R,2S)-2-aminocyclopentanecarboxylate hydrochloride; Methyl (1S,2R)-2-aminocyclopentanecarboxylate hydrochloride; trans-2-Aminocyclopentanecarboxylic acid methyl ester hydrochloride; Methyl trans-2-aminocyclopentanecarboxylate hydrochloride; (1R,2S)-2-Aminocyclopentanecarboxylic acid methyl ester hydrochloride; (1S,2R)-2-Aminocyclopentanecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our trans-Methyl 2-Aminocyclopentanecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.