Description

2-Acetamido-2-Deoxy-3-o-(2-o-Sulfo-β-D-Gluco-4-Enepyranosyluronic Acid)-4-o-Sulfo-D-Galactose, 3Na is a highly sulfated, complex disaccharide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical intermediate and reference standard for studying glycosaminoglycan (GAG) structure, function, and metabolism. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on heparin/heparan sulfate analytics, enzyme substrate development, and carbohydrate-based drug discovery.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the identification and quantification of heparin and heparan sulfate-derived oligosaccharides via analytical techniques like HPLC and mass spectrometry.
• Enzyme Substrate & Inhibitor Studies: Acts as a specific substrate or inhibitor for sulfatases, glycosidases, and other enzymes involved in GAG catabolism and signaling pathways.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel carbohydrate-based therapeutics, including anticoagulants and anti-inflammatory agents.
• Diagnostic Reagent Development: Employed in the development of diagnostic assays and kits for monitoring GAG-related metabolic disorders (e.g., mucopolysaccharidoses).
• Glycomics & Proteomics: A vital tool for glycan array fabrication and studies investigating carbohydrate-protein interactions critical to cell signaling and disease mechanisms.
• Quality Control in Heparin Production: Utilized as a process control standard to ensure the consistency and safety of heparin API manufacturing.

Basic Information

Product Name	2-Acetamido-2-Deoxy-3-o-(2-o-Sulfo-β-D-Gluco-4-Enepyranosyluronic Acid)-4-o-Sulfo-D-Galactose, 3Na
CAS No.	136132-71-3
Molecular Formula	C14H19NNa3O19S2
Molecular Weight	694.44 g/mol
Synonyms	δUA-GlcNS-6S-GalNAc-4S, Sodium Salt; 3-O-(2-O-Sulfo-β-D-gluco-4-enepyranosyluronic acid)-2-acetamido-2-deoxy-4-O-sulfo-D-galactose trisodium salt; Heparin Disaccharide II-S Trisodium Salt; 2-Acetamido-2-deoxy-3-O-(2-O-sulfo-β-D-gluco-4-enepyranosyluronic acid)-4-O-sulfo-D-galactose trisodium salt; N-Acetylheparosan disaccharide I-S trisodium salt; HS Disaccharide 2S trisodium salt; Unsaturated Heparin Disaccharide δUA-GlcNS-6S-α1-4-GalNAc-4S.
EINECS	Contact for details

Quality Control

Our 2-Acetamido-2-Deoxy-3-o-(2-o-Sulfo-β-D-Gluco-4-Enepyranosyluronic Acid)-4-o-Sulfo-D-Galactose, 3Na is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) specifying batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at low temperature. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
pH (1% Solution)	5.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.