Description

6'-n-Acetylneuraminyl-n-Acetyllactosamine, Sodium is a high-purity, chemically defined sialylated oligosaccharide derivative. This compound serves as a critical reference standard and intermediate in advanced glycobiology research and biopharmaceutical development. It is essential for researchers and manufacturers in the fields of vaccinology, therapeutic antibody production, and diagnostic assay development, where precise glycan structures are required for studying cell-cell interactions, pathogen recognition, and drug targeting.

Application

• Glycobiology Research: Used as a reference standard and substrate for studying sialyltransferase and neuraminidase (sialidase) enzyme activity and specificity.
• Biopharmaceutical Development: Serves as a key intermediate or standard in the synthesis and quality control of complex glycoproteins, including monoclonal antibodies and recombinant vaccines.
• Diagnostic Reagents: Employed in the development of assays for detecting pathogens or antibodies that bind specifically to sialylated glycans, such as influenza viruses.
• Cell Biology Studies: Applied in research on cell surface recognition, signaling, and adhesion processes mediated by sialic acid-containing structures.
• Enzyme Inhibitor Screening: Acts as a substrate in high-throughput screens for identifying inhibitors of glycosyltransferases or glycosidases relevant to disease.
• Nutritional Science: Investigated as a potential bioactive component, given its structural similarity to human milk oligosaccharides (HMOs).

Basic Information

Product Name	6'-n-Acetylneuraminyl-n-Acetyllactosamine, Sodium
CAS No.	136098-09-4
Molecular Formula	C31H51N3O23•Na
Molecular Weight	872.73 g/mol
Synonyms	Sodium 6'-Sialyllactosamine; 6'-SLN, Sodium salt; 6'-O-(N-Acetyl-α-neuraminyl)-N-acetyllactosamine sodium salt; Neu5Acα2-6Galβ1-4GlcNAc sodium salt; Sialyl Lewis x precursor; 6'-N-Acetylneuraminyllactosamine sodium; LST a sodium salt; 6'-Sialyl-N-acetyllactosamine
EINECS	Contact for details

Quality Control

Every batch of 6'-n-Acetylneuraminyl-n-Acetyllactosamine, Sodium is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (NMR, MS), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.