Description

Methyl 4-Carbamoylbicyclo[2.2.2]Octane-1-Carboxylate is a high-value, synthetically versatile bicyclic organic compound. It serves as a critical advanced pharmaceutical intermediate and a sophisticated building block in complex organic synthesis. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring a rigid, three-dimensional bicyclo[2.2.2]octane scaffold for enhanced binding affinity and metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the bicyclic structure can impart unique biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis, leveraging its defined stereochemistry and functional handles.
• Material Science Monomer: Potential building block for high-performance polymers and resins, where its rigid structure can enhance thermal stability and mechanical properties.
• Academic & Industrial R&D: Employed in methodological chemistry research and discovery chemistry for constructing complex natural product analogs and novel chemical entities.

Basic Information

Product Name	Methyl 4-Carbamoylbicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	135908-42-8
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	1-Carbomethoxy-4-carbamoylbicyclo[2.2.2]octane; Methyl 1-Carbamoylbicyclo[2.2.2]octane-4-carboxylate; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-carbamoyl-, methyl ester; 4-Carbamoylbicyclo[2.2.2]octane-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Carbamoylbicyclo[2.2.2]Octane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.