Description

6-Fluoroquinolin-8-Ol is a high-purity fluorinated quinoline derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in the strategic incorporation of fluorine and hydroxyl groups, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated quinolone antibiotics and other bioactive molecules targeting bacterial, viral, or oncological pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides where the fluorine atom enhances efficacy and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for complex heterocyclic compounds, ligands for catalysis, and functionalized materials via its reactive hydroxyl and fluorine sites.
• Material Science: Potential monomer or additive for creating specialty polymers, liquid crystals, or organic electronic materials with tailored optical and electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	6-Fluoroquinolin-8-Ol
CAS No.	135838-04-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	8-Hydroxy-6-fluoroquinoline; 6-Fluoro-8-hydroxyquinoline; 6-Fluoro-8-quinolinol; 6-Fluoroquinolin-8-ol; 135838-04-9; 6-Fluoro-8-quinolol; 8-Quinolinol, 6-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinolin-8-Ol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.