Description

Carbamic Acid, (3-Chlorocyclobutyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring a chlorinated cyclobutane ring, which is of significant interest in advanced synthetic chemistry. This compound serves as a key protected intermediate for the synthesis of novel pharmacologically active molecules, particularly in the development of constrained analogs and conformationally restricted scaffolds. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a chlorocyclobutyl moiety.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce conformational constraints and explore new chemical space.
• Process Chemistry Development: Serves as a starting material or intermediate in the development and scale-up of synthetic routes for complex organic molecules.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents and herbicides.
• Material Science Research: Can be investigated as a monomer or precursor for the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	Carbamic Acid, (3-Chlorocyclobutyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	135767-83-8
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	tert-Butyl (3-chlorocyclobutyl)carbamate; N-(tert-Butoxycarbonyl)-3-chlorocyclobutanamine; 3-Chlorocyclobutanamine, N-BOC-protected; BOC-3-Chlorocyclobutylamine; N-Boc-3-chlorocyclobutanamine; 1,1-Dimethylethyl N-(3-chlorocyclobutyl)carbamate; (3-Chlorocyclobutyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Chlorocyclobutyl)-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.