Description

6-Bromo-3,4-Dihydro-4,4-Dimethylquinolin-2(1H)-One is a high-purity brominated quinolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and researchers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and plant growth regulators due to its bioactive quinolinone core.
• Material Science Precursor: Serves as a monomer or functional unit in the development of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe to investigate biological pathways.
• Academic & Contract Research: Essential reagent for universities and contract research organizations (CROs) engaged in synthetic methodology development and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-3,4-Dihydro-4,4-Dimethylquinolin-2(1H)-One
CAS No.	135631-90-2
Molecular Formula	C₁₁H₁₂BrNO
Molecular Weight	254.12 g/mol
Synonyms	6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone; 2(1H)-Quinolinone, 6-bromo-3,4-dihydro-4,4-dimethyl-; 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-Dihydro-4,4-Dimethylquinolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee full traceability and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.