Description

trans-3-Oxabicyclo[3.1.0]Hexane-6-Methanol is a high-value, bicyclic oxirane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique fused oxabicyclo[3.1.0]hexane scaffold provides a rigid, three-dimensional framework essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including protease inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized polymers and advanced materials with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and new reaction development.

Basic Information

Product Name	trans-3-Oxabicyclo[3.1.0]Hexane-6-Methanol
CAS No.	135577-15-0
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	(1R,5S,6r)-6-(Hydroxymethyl)-3-oxabicyclo[3.1.0]hexane; (1R,5S,6r)-3-Oxabicyclo[3.1.0]hexane-6-methanol; trans-6-Hydroxymethyl-3-oxabicyclo[3.1.0]hexane; Bicyclo[3.1.0]hexane-6-methanol, 3-oxa-, (1R,5S,6r)-rel-; Oxabicyclohexane methanol derivative; Chiral oxirane fused cyclohexanol
EINECS	Contact for details

Quality Control

Our trans-3-Oxabicyclo[3.1.0]Hexane-6-Methanol is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects with custom purity grades, including research, technical, and GMP-compliant material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.