Description

3β-(4-Iodophenyl)Tropane-2β-Carboxylic Acid Methyl Ester is a high-purity synthetic organic compound belonging to the tropane alkaloid class, serving as a critical intermediate in advanced pharmaceutical research and development. Its value lies in its specific structural configuration, which makes it a key building block for synthesizing novel compounds targeting the central nervous system. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery programs and analytical reference standards.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel tropane-based therapeutic agents and diagnostic tools.
• Neuroscience Research: Used as a reference standard or building block in studies targeting neurotransmitter transporters, particularly dopamine and serotonin transporters.
• Radiopharmaceutical Development: Serves as a precursor for iodinated or radiolabeled (e.g., with I-123 or I-125) compounds used in Positron Emission Tomography (PET) or Single-Photon Emission Computed Tomography (SPECT) imaging agents.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new molecules with potential psychostimulant or therapeutic properties.
• Analytical Standard: Used as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Biochemical Tool Compound: Utilized in in vitro assays to study binding affinity and inhibition kinetics at specific biological targets.

Basic Information

Item	Detail
Product Name	3β-(4-Iodophenyl)Tropane-2β-Carboxylic Acid Methyl Ester
CAS No.	135367-08-7
Molecular Formula	C17H20INO2
Molecular Weight	397.25 g/mol
Synonyms	3β-(4-Iodophenyl)tropane-2β-carboxylic acid methyl ester; Methyl 3β-(4-iodophenyl)-2β-tropanecarboxylate; β-CIT methyl ester; 2β-Carbomethoxy-3β-(4-iodophenyl)tropane; RTI-55 methyl ester; Nor-β-CIT methyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3β-(4-Iodophenyl)Tropane-2β-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.