Description

3-Oxatricyclo[3.2.1.02,4]Octane-6-Carboxylicacid,[1R-(1Alpha,2Beta,4Beta,5Alpha,6Alpha)]-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its rigid, complex tricyclic oxa-cage structure, which serves as a critical chiral building block in organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated scaffold or precursor in catalytic asymmetric reactions to introduce complex stereochemistry.
• Medicinal Chemistry Research: Serves as a core structure for constructing compound libraries in drug discovery programs targeting specific biological pathways.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands or organocatalysts due to its unique three-dimensional geometry.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of high-value, complex specialty chemicals and fragrances.

Basic Information

Product Name	3-Oxatricyclo[3.2.1.02,4]Octane-6-Carboxylicacid,[1R-(1Alpha,2Beta,4Beta,5Alpha,6Alpha)]-(9Ci)
CAS No.	135357-67-4
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1R,2S,4S,5R,6R)-3-Oxatricyclo[3.2.1.02,4]octane-6-carboxylic acid; (1R,5R,6R)-3-Oxatricyclo[3.2.1.02,4]octane-6-carboxylic acid; endo-3-Oxatricyclo[3.2.1.02,4]octane-6-carboxylic acid; Tricyclic oxa-cage carboxylic acid; 135357-67-4; (1R,2S,4S,5R,6R)-6-Carboxy-3-oxatricyclo[3.2.1.02,4]octane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch is characterized and tested to ensure high chemical and chiral purity. Comprehensive analytical data, including HPLC, NMR, and optical rotation, is provided. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting your quality by design (QbD) and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.