Description

(R)-2-Methylpyrrolidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Synthesis: Employed in the manufacture of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Process R&D: Serves as a valuable reagent in university and industrial laboratories for method development and scale-up studies.
• Fine Chemical Production: Integral to the synthesis of complex, high-value specialty chemicals requiring the (R)-configured pyrrolidine scaffold.

Basic Information

Product Name	(R)-2-Methylpyrrolidine Hydrochloride
CAS No.	135324-85-5
Molecular Formula	C5H12ClN
Molecular Weight	121.61 g/mol
Synonyms	(R)-2-Methylpyrrolidine HCl; (R)-2-Methylpyrrolidine hydrochloride; (R)-2-Methyl-1-azacyclopentane hydrochloride; (R)-α-Methylpyrrolidine hydrochloride; (2R)-2-Methylpyrrolidine hydrochloride; (R)-(-)-2-Methylpyrrolidine hydrochloride; Pyrrolidine, 2-methyl-, hydrochloride, (2R)-; L-2-Methylpyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Methylpyrrolidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is subjected to comprehensive analytical testing, including chiral purity assessment by HPLC. Certificates of Analysis (COA) detailing specific results for identity, assay, enantiomeric excess, and impurities are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.