Description

5-(n-tert-Butoxycarbonylamino)Salicylic Acid is a protected amino acid derivative that serves as a crucial building block in advanced organic synthesis. This compound is valued for its role in introducing the salicylic acid moiety while protecting the amine functionality, enabling complex multi-step reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and production of novel drug candidates, particularly in anti-inflammatory and analgesic research.
• Peptide Synthesis: Used as a protected amino acid component in solid-phase and solution-phase peptide synthesis.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced crop protection agents and herbicides.
• Bioconjugation Chemistry: Facilitates the creation of antibody-drug conjugates (ADCs) and other targeted therapeutic molecules.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Fine Chemical Synthesis: A versatile intermediate for creating complex organic molecules in custom synthesis projects.

Basic Information

Product Name	5-(n-tert-Butoxycarbonylamino)Salicylic Acid
CAS No.	135321-95-8
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]-2-hydroxybenzoic Acid; 5-(Boc-amino)salicylic Acid; Boc-5-ASA; 5-Amino-2-hydroxybenzoic Acid N-Boc Derivative; 2-Hydroxy-5-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic Acid; 5-(tert-Butoxycarbonylamino)salicylic Acid; N-Boc-5-aminosalicylic Acid; 5-(Boc-NH)-SA
EINECS	Contact for details

Quality Control

Our 5-(n-tert-Butoxycarbonylamino)Salicylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.