Description

3-Quinolinepropanoicacid,-α--Amino-,(-α-R)-(9Ci) is a high-purity chiral amino acid derivative featuring a quinoline scaffold. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials. The compound, with CAS No. 135213-89-7, is supplied to meet the stringent requirements of process chemistry and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly those targeting neurological or infectious diseases.
• Agrochemical Research: Used in the development of novel, optically active pesticides and herbicides where the quinoline moiety imparts specific biological activity.
• Ligand Synthesis: Acts as a precursor for the preparation of chiral ligands used in asymmetric catalysis, such as organocatalysts or metal-complexing agents.
• Peptidomimetics & Conjugate Chemistry: Incorporated into the design of peptide analogs and bioconjugates to modify pharmacokinetic properties or introduce fluorophores.
• Academic & Process R&D: Employed in methodological studies and scale-up process development for fine chemical manufacturing.

Basic Information

Item	Detail
Product Name	3-Quinolinepropanoicacid,-α--Amino-,(-α-R)-(9Ci)
CAS No.	135213-89-7
Molecular Formula	C₁₂H₁₂N₂O₂
Molecular Weight	216.24 g/mol
Synonyms	(R)-2-Amino-3-(quinolin-3-yl)propanoic acid; (αR)-α-Amino-3-quinolinepropanoic acid; D-3-Quinolylalanine; (R)-3-Quinolylalanine; 3-Quinolin-3-yl-D-alanine; (R)-2-Amino-3-(3-quinolyl)propionic acid; β-(3-Quinolyl)-D-alanine
EINECS	Contact for details

Quality Control

Our 3-Quinolinepropanoicacid,-α--Amino-,(-α-R)-(9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, enantiomeric excess, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.