Description

4-Chloro-5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidin-2-Amine is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical synthetic precursor for the development of novel pharmacologically active molecules, particularly in medicinal chemistry. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to accelerate the discovery and production of new drug candidates targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways and target validation.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science: Exploration as a precursor for nitrogen-doped carbon materials or specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-Chloro-5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidin-2-Amine
CAS No.	135196-93-9
Molecular Formula	C7H9ClN4
Molecular Weight	184.63 g/mol
Synonyms	4-Chloro-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-amine; 2-Amino-4-chloro-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine; 4-Chloro-5,6,7,8-tetrahydro-2-pyrido[2,3-d]pyrimidinamine; 4-Chloro-2-amino-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine; 135196-93-9; 4-Chloro-2-aminotetrahydropyrido[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to meet the stringent requirements of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.