Description

4-Amino-3,5-Difluoro-Phenol is a high-purity fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and phenolic functional groups on a difluorinated benzene ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve thermal stability, chemical resistance, and surface properties.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing advanced fluorinated dyes and colorants.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Amino-3,5-Difluoro-Phenol
CAS No.	135086-76-9
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	3,5-Difluoro-4-hydroxyaniline; 4-Hydroxy-3,5-difluoroaniline; 4-Amino-2,6-difluorophenol; 2,6-Difluoro-4-aminophenol; Phenol, 4-amino-3,5-difluoro-; ADFP
EINECS	Contact for details

Quality Control

Our 4-Amino-3,5-Difluoro-Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting full specifications are available upon request, providing transparency and traceability for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.