Description

4-tert-Butoxyphenylacetic Acid is a versatile aromatic carboxylic acid derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butoxy substituent, which provides steric bulk and can act as a protecting group or a directing moiety in complex molecular constructions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is utilized in the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its phenylacetic acid core is incorporated into bioactive molecules.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays, contributing to the molecular structure of liquid crystals.
• Organic Synthesis Reagent: Employed in coupling reactions, such as Suzuki or Heck reactions, and as a starting material for preparing more complex esters and amides.
• Polymer Additive Precursor: Used to synthesize modifiers and stabilizers that enhance the properties of engineering plastics and high-performance polymers.
• Chemical Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-tert-Butoxyphenylacetic Acid
CAS No.	135066-21-6
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	p-(tert-Butoxy)phenylacetic Acid; 4-(tert-Butoxy)benzeneacetic Acid; (4-tert-Butoxyphenyl)acetic Acid; 2-(4-tert-Butoxyphenyl)acetic Acid; 4-tert-Butoxybenzeneacetic Acid; 4-(1,1-Dimethylethoxy)benzenacetic Acid; 4-tert-Butoxyphenyl Acetic Acid; p-tert-Butoxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 4-tert-Butoxyphenylacetic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.