Description

2-(2-(2-Aminoethoxy)Ethoxy)Acetic Acid Hydrochloride is a specialized organic salt featuring a polyether linker terminated with an amino group and a carboxylic acid. This compound matters as a versatile, water-soluble building block for the synthesis of complex molecules, offering a reactive handle for conjugation and modification. It is primarily needed by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing drug delivery systems, diagnostic agents, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring PEG-like spacers.
• Bioconjugation Linker: Used to covalently attach drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles for targeted therapies and diagnostics.
• Polymer Chemistry: Serves as a monomer or functional initiator for creating specialized polyethers, dendrimers, and smart hydrogels with tailored properties.
• Surface Modification: Employed to functionalize material surfaces (e.g., gold, silica) with carboxylic acid groups for subsequent biomolecule immobilization.
• Chelating Agent Synthesis: Acts as a starting material for synthesizing novel chelators used in medical imaging and metal ion scavenging.
• Cross-linking Agent: Facilitates the formation of covalent bonds between molecules in the development of stable matrices for tissue engineering or chromatography.

Basic Information

Product Name	2-(2-(2-Aminoethoxy)Ethoxy)Acetic Acid Hydrochloride
CAS No.	134979-01-4
Molecular Formula	C8H18ClNO5
Molecular Weight	243.68 g/mol
Synonyms	8-Amino-3,6-dioxaoctanoic Acid Hydrochloride; 2,2'-Ethylenedioxydi(ethylamine)acetic Acid Hydrochloride; O2O'-Bis(2-aminoethyl)ethylene glycol-N-acetic Acid Hydrochloride; Amino-PEG2-acetic Acid Hydrochloride; H2N-PEG2-CH2COOH·HCl; AEEA-Acetic Acid HCl; 2-[2-(2-Aminoethoxy)ethoxy]acetic Acid Hydrochloride; 8-Amino-3,6-dioxaoctanoic Acid HCl
EINECS	Contact for details

Quality Control

Our 2-(2-(2-Aminoethoxy)Ethoxy)Acetic Acid Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.