Description

Phenol, 5-(1-Aminoethyl)-2-Methoxy-, (R)- is a chiral aromatic amine derivative of methoxyphenol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its defined stereochemistry, which is essential for creating enantiomerically pure compounds with specific biological activities. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry impacts efficacy and environmental profile.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in catalytic processes to induce stereoselectivity.
• Fine Chemical Production: Serves as a building block for advanced materials, liquid crystals, and specialty polymers requiring precise molecular architecture.
• Biochemical Research: Utilized in proteomics and enzyme studies as a modifier or probe due to its phenolic and amine functional groups.

Basic Information

Product Name	Phenol, 5-(1-Aminoethyl)-2-Methoxy-, (R)-
CAS No.	134856-00-1
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	(R)-5-(1-Aminoethyl)-2-methoxyphenol; (R)-2-Methoxy-5-(1-aminoethyl)phenol; (R)-Hordenine precursor; (R)-O-Methyltyrosamine; 1-(4-Hydroxy-3-methoxyphenyl)ethylamine, (R)-; (R)-1-(4-Hydroxy-3-methoxyphenyl)ethanamine; (R)-4-(1-Aminoethyl)-2-methoxyphenol
EINECS	Contact for details

Quality Control

Our Phenol, 5-(1-Aminoethyl)-2-Methoxy-, (R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.