Description

(R)-4-(1-Aminoethyl)Phenol (S)-Hydroxybutanedioate Salt is a high-purity chiral intermediate and resolving agent. This compound is critical for the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, ensuring high stereoselectivity in complex reactions. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and advanced material sectors for developing active pharmaceutical ingredients (APIs) and specialty compounds.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures in pharmaceutical synthesis.
• Pharmaceutical Intermediate: A key building block for the production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis Catalyst: Employed in catalytic processes to induce chirality in target molecules.
• Agrochemical Research: Serves as an intermediate in the development of chiral pesticides and herbicides.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for research in organic chemistry and process development.

Basic Information

Product Name	(R)-4-(1-Aminoethyl)Phenol (S)-Hydroxybutanedioate Salt
CAS No.	134855-89-3
Molecular Formula	C12H17NO6
Molecular Weight	271.27 g/mol
Synonyms	(R)-4-(1-Aminoethyl)phenol (S)-2-hydroxybutanedioate; (R)-1-(4-Hydroxyphenyl)ethylammonium (S)-hydrogen malate; (R)-p-Hydroxy-α-methylbenzylamine (S)-hydrogen malate; (R)-4-(1-Aminoethyl)phenol malate (S-form); (R)-HMPA (S)-malate; AR-HMPA (S)-malate salt; (R)-1-(4-Hydroxyphenyl)ethanaminium (S)-2-hydroxybutanedioate
EINECS	Contact for details

Quality Control

Our (R)-4-(1-Aminoethyl)Phenol (S)-Hydroxybutanedioate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.