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Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium (Ii) CAS NO 134524-84-8


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CAS No.:134524-84-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium (II) is a high-value, chiral ruthenium complex widely recognized as a highly efficient and enantioselective catalyst. This compound is critical for enabling asymmetric synthesis, a cornerstone of modern pharmaceutical and fine chemical manufacturing. It is primarily sought after by research institutions and industrial chemists developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise stereochemical control is paramount.

Application

  • Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
  • Pharmaceutical Intermediate Synthesis: Key for constructing complex, single-enantiomer molecules used in drug discovery and development for APIs.
  • Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators with enhanced biological activity.
  • Fine Chemical Production: Enables the production of high-value chiral flavors, fragrances, and specialty polymers.
  • Academic & Industrial R&D: A standard reagent in methodological development for new catalytic asymmetric transformations.
  • Process Chemistry Optimization: Employed for scaling up enantioselective routes from laboratory to pilot and commercial production.

Basic Information

Product Name Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Ruthenium (II)
CAS No. 134524-84-8
Molecular Formula C44H32Cl2P2Ru
Molecular Weight 792.66 g/mol
Synonyms (R)-RuBINAP Dichloride; Dichloro[(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium; (R)-BINAP-RuCl2; [RuCl2((R)-BINAP)]; RuCl2[(R)-BINAP]; (R)-BINAP-Ru(II) Dichloride; Ruthenium(II) (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl Dichloride; (R)-BINAP-Ru Catalyst
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Quality Control

Our Dichloro[(R)-(+)-BINAP]Ruthenium (II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and residual solvent content is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is easily oxidized and light-sensitive (store away from light). Allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance Reddish-brown to purple crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Elemental Analysis (C, H) Within theoretical ± 0.4%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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